Neglected Diseases Research And Development 2

Neglected Diseases


Neglected diseases are communicable bacterial, parasitic and viral diseases that mainly affect world’s poor populations inhibiting tropical and subtropical countries. Examples of such diseases include; Ascariasis– Which is an infection of the semi-colon resulting from attack by Ascaris lumbricoides; Chagas disease– a highly infectious condition caused by a parasite found on triatomine bug faeces; Schistosomiasis– a condition caused by freshwater worms mainly found in the subtropical and tropical countries and Leprosy– Which is a chronic and curable highly infectious disease which causes nerve damage and skin lesions (Steward, et al, 2007).

Neglected diseases research is a research done to develop on the diverse diseases that cause illness and at the same time hamper economic growth in regions inhabited by poor persons/societies. It is carried out in support the World Health Organization’s control strategy directed to such diseases (“Neglected tropical disease (NTD) research”, 2018).

Challenges encountered in researching and development of new medicines

Laboratory issues

Research on neglected diseases requires high standard diagnostic equipment which most of the times goes with huge investment. Since the regions attacked by these diseases are defined by poverty, such equipment becomes a challenge to procure as the available health facilities are low class and do not have the capacity to acquire such equipment (Ravinetto et al., 2018).

Human resources

Human knowledge, skills and, force are required for the research to get on but it faces a challenge since neglected diseases are highly communicable and a mini exposure gets one infected with them. If a member of the team carrying out the research falls sick, then the whole process is affected and hence their output is affected too (Ravinetto et al., 2018).

Management of research projects

Project management skills are essential for any research project and this brings in the sense of having qualified professionals to carry out management tasks. Therefore since neglected diseases research is mostly done in poor regions which are prone to the condition. Such areas lack right quality equipment required to effect the research hence its management is challenged (Ravinetto et al., 2018).

Protection of Communities

Neglected diseases attack areas with low standards of living with fragile health facilities which mean that access to right quality healthcare which can help protect the community from the diseases is compromised. Consequently, the poor households are frequently trying to secure the unavailable health facilities and hence do not pay attention to identifying research-related risks which leave researchers exposed to all dangers emerging from neglected diseases (Ravinetto et al., 2018).

Good Clinical Practice Implementation

GCLP is a set of standards that guide on implementing ethical clinical practice as stated by the nursing society. In research on neglected diseases implementation of such standards is a challenge as there is not enough funding, enough human resources and the environmental care mechanisms are poor. Such facts about the poor tropical and subtropical countries make it a challenge to carry out a quality research on neglected diseases (Ravinetto et al., 2018).

Describe the markets and incentives involved to encourage the development of medications

Prizes and presents

They are target prizes presented to researchers as an appreciation of their effort and devotion towards the research and presenting a credible output. It is given as a form of an incentive directed towards encouraging a researcher to execute his or her responsibilities devotedly (Mueller-Langer, 2018).

Publicly funded research institutions

Public resources are directed to research institutions which are mandated to research and develop on medications for neglected diseases. Such funding serves to strengthen the institutions as they can afford required diagnosis facilities and even set up the required healthcare units on the affected regions (Mueller-Langer, 2018).

Research and development tax credits

These are direct state contribution towards pharmaceutical companies which serves to back up their efforts towards addressing the issue. Such taxes, therefore, finance the research inputs which help to see the quality and ethical research output (Mueller-Langer, 2018).

Discuss current debates and controversies encountered by the Global Health community

Across global lines, there have been efforts to achieve regional balance through even distribution of national resources which is meant to see that areas inhabited by poor populations have the right standards of facilities set up for them by the state. Although this has been there for years there are no positive outcomes with debated affirming that it is not possible for the current corrupt regimes to see the initiative succeeding (“Global Issues Overview”, 2018).

Food for thought, since neglected diseases affect closely all tropical and subtropical regions, efforts towards controlling the conditions needs international efforts.

Recommendations that could be applied by the Ministry of Health

The Ministry of Health should on coming up with an international initiative towards researching and developing on neglected diseases as they are a global threat. With such a dimension they will be able to effectively tackle the health issue which for the longest spell has affected living in subtropical and tropical countries.


Global Issues Overview. (2018). Retrieved 6 February 2018, from

Mueller-Langer, F. (2018). Neglected infectious diseases: Are push and pull incentive mechanisms suitable for promoting drug development research?. Retrieved 6 February 2018, from

Neglected tropical disease (NTD) research. (2018). World Health Organization. Retrieved 6 February 2018, from

Ravinetto, R., Alirol, E., Mahendradhata, Y., Rijal, S., Lutumba, P., & Sacko, M. et al. (2018). Clinical Research in Neglected Tropical Diseases: The Challenge of Implementing Good Clinical (Laboratory) Practices. Retrieved 6 February 2018, from

Steward, R., Bueno de Mesquita, J., Oldring, L., & Hunt, P. (2007). Neglected diseases. Geneva, Switzerland: World Health Organization.